THE USE OF Aspergillus nidulans TEST SYSTEM FOR THE RECOMBINOGENIC ACTIVITY OF ENVIRONMENTAL FACTORS

Resumen

A test system, based on the parasexual cycle of Aspergillus nidulans for the detection of the recombinogenic activity of enviromental factors is described. The use of diploid strain heterozygous for nutritional requirements and spore colour enables the identification of recombinants formed by mitotic crossing-over or non-disjunction. A diploid strain is especially described which provides information about the mechanisms of the recombinogenicity of various chemical factors by simple genetic analysis of the colour segregants induced by such factors.